Microbiology and Immunology 2500A/B Study Guide - Sanofi Pasteur, Vaxgen, Exonuclease
3 May 2014
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Course: viral infectious cycle, viral structure, viral entry, viral pathogenesis, hiv pathogenesis & vaccines. Ex. measles virus: most infectious virus, very contagious. Probs eat it daily (insect viruses on vegetables) Most viruses that infect us don"t cause disease. 3 levels of defense mechanisms (intrinsic, innate immunity, acquired immunity) Wasp genes carried by the polydnavirus virions suppress innate immune response of larva/caterpillar (wasp lays eggs inside caterpillar + virions) allowing development of eggs virus helps a fungus. Fungus permits plant survival but fungus can"t grow >50 c. virus allows thermotolerance virus making nicer flowers (broken tulip b/c of potyvirus) It orchestrates synthesis of all req elements: 1950s: established that viral genome is the genetic code. Viruses must make mrna that can be translated by host ribosomes. Can only function after they replicate in host cell machinery to make viral proteins. No virus can translate proteins from mrna on their.
