KINESIOL 1Y03 Chapter Notes -Zona Pellucida, Inner Cell Mass, Conjoined Twins

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Head of the sperm has structure called acrosome, which as digestive enzyme that help digest through the membrane layer. Flagella used to propell towards the cron radiata and oocyte plasma membrane. The once that reach near zona pellucidta, specific receptor zp3 binding with sperm. The sperm acrosomal cap binds to zp3 and its called acrosomal reaction. Activation of digestive enzymes that break down the membrane of zona pellucida. Actually takes quite a few secretion of many sperms to weaken the zona pellucida membrane enough to let one sperm through. First member that makes it through zona pellucida envounters plasma membrane of the oocyte. There is another receptor integrin a6b1 that immediately causes depolarization. Change of electric potential across plasma membrane that shocks away other sperms from attaching to plasma membrane. Positive calcium ions released outside, movement brings along water from the inside of the cell. Oocyte itself starts to shrink, so there is space between zona pleuicida and plasma membrane.

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