MIP 300 Lecture Notes - Crystal Violet, Tetrapeptide, Prokaryote

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Membranes are an absolute requirement for all living cells, both eukaryotic and prokaryotic. Location of metabolic processes (photosynthesis, oxidative phosphorylation) and chemotaxis receptors. Glycoproteins: covalently attached oligosaccharides, either peripheral or integral. Nutrient and waste transport into and out of cell. This model of membrane structure is called the fluid mosaic model. Envelope consists of all structures outside of plasma membrane. Most bacteria except mycoplasmas and a few archeobacteria contain a cell wall. Except for mycobacterium, bacteria have either gram + or cell wall, waxy layer of mycolic acid inhibits good staining. Most bacteria live in a hypotonic environment (less solutes in environment than cell), osmosis, water would rush in, break cell. Large periplasmic space between plasma membrane and outer membrane. Large # of periplasmic enzymes involved in nutrient acquisition, permeases, hydrolytic enzymes. Porin proteins allow small molecules to pass (more permeable than plasma membrane) This makes it hard for the immune system to deal with.

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