Biology 1001A Lecture Notes - Single-Nucleotide Polymorphism, Comparative Genomics, Reverse Transcriptase
5 Jul 2014
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Differences among insertion sequences, transposons, & retrotransposons: transposable elements segments of dna that can move from one place to another. Insertion sequences: simplest te, relatively small, only contains genes for transposase, catalyzes recombination of tes. Classified as recombinase, makes cuts in dna backbone: inverted repeat sequence: repeated sequence of dna on either side of is running in opposite directions. This enables transposase enzyme to identify the ends of te when it catalyzes transposition: have an inverted repeat sequence at each end, enclosing a central region w, transposons: 1(+) genes movement of element: in many bacteria, the inverted repeats as is which contain transposase for, transposons carry genes for antibiotic resistance; originate from bacterial chromosome or plasmids; greatly incr. spread of genes. Lecture 9 origin of variation: transposons: similar to bacterial transposons, retrotransposons, transposition occurs via an intermediate rna copy to te. Reverse transcriptase uses rna template to make dna copy of.
