BPS 1101 Study Guide - Informed Consent, Animal Testing, Theralizumab

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What happens to a drug in your body: very complex, and when companies work to develop drugs, there is a large amount of time spent on how the drug gets in/changes. Durgs pass many barriers entering the body: turning the material into a product you can sell is very difficult, getting chemicals into the body is very hard. It has to pass through barriers, and it removes part of the drug. The more barrieris you have, the fewer amount of drug will go in or will not go in at all. Most drufs pass through digestive system: deal with 3 organs, sometimes kidney, but the stomach, intestine and the liver, companies spend a lot of time worrying about how ti will go through these areas. The stomach is the first barrier: drug must survive acid. Sicne acids are corrosive and destroy things, the substance you are taking must have to survive the stomach.

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