BIOL308 Lecture Notes - Rna Polymerase Ii, Tata Box, Transcription Factor Ii F
16 Jul 2014
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Document Summary
One gene could be transcribed in response to multiple conditions. Heat shock protein (s) - important for cell protection - are expressed when cells are exposed to high temperature and heavy metals. Different conditions are associated with different cis elements which bind different regulatory proteins (transcription factors) Gene that responds to multiple conditions has multiple cis elements (4 in gene a, 3 in gene b) There are a heat shock response element (hre) and metal responsive element (mre) in promoter regions of genes for heat shock proteins. Certain signal/condition could increase and/or decrease transcription of different genes. Different genes which respond to the same signal in the same way all have the same cis element. Orange element #3 in promoters of genes a and b. There is no consistent location of cis element(s) among different genes. Orange element #3 in different locations relative to genes a and b.
