BIO207H5 : cheatsheet1.docx

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20 Jul 2014
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Autosomal dominant: (cid:0) across a population, the proportion of affected males should be equal to the proportion of affected females. (cid:0) male-to-male transmission can be observed. Autosomal recessive parents of an affected individual are not affected but are gene carriers. X-linked dominant (cid:0) males more severely affected (some lethal) (cid:0) male is affected, all his daughters will be affected, but none of his sons will be affected. X-linked recessive (cid:0) affected males: all of their daughters, who are then carriers, but to none of their sons (cid:0) women are affected when they have two copies of the disease allele. All of their sons will be affected, and all of their daughters will be unaffected carriers. Mitochondrial/cytoplasmic only inherited from the mother"s egg, thus only females can transmit the trait to offspring and they pass it on to all of their offspring. Biosynthetic pathways are networks of interacting genes that produce a molecular compound as their endpoint.

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