BIOL240 Lecture Notes - Prokaryote, Archaea, Molecular Phylogenetics
13 Sep 2014
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First, remember that genomes are continually mutating and evolving. This involves continual changes in dna sequence. If two organisms had a common ancestor, the difference in their genome sequence would be an indication of their evolutionary relatedness. It is sufficient to compare homologous sequences, or molecular chronometers, that are found in both of the organisms. Within the length of ~1500 nucleotides there are both highly conserved and highly variable regions. Dna of the organism (figure 16. 12). That pcr product can then be sequenced directly. The use of rrna sequences has revolutionized the science of microbiology. First, it has re- ordered our understanding of how the different life forms on earth are related. Second, we are now able to probe the microbial community structure of environments without first culturing the organisms. Through such studies, it has become very. Dr. josh d. neufeld apparent that almost all environments contain microorganisms that have never been cultured and described before.
