BIOA01H3 Lecture Notes - Ribonucleotide, Nitrogenous Base, Intron
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Exon- region of the primary transcript that might be part of the final transcript of. Intron- region of the primary transcript that are never part of the final transcript if there is no mistake. Sometime have a regulatory role in gene expression of other genes. 5" utr 3"utr- doesn"t contain info for translation to make protein. Poly(a)tail- small polymer with nucleotides that have adenine, the tail is created separately. Gets added on enzymatically, cleaves off backend of mmrna(stimulates rna polymerase to get out). Splisosomes: cut out introns, complex structure in rna and protein components. Splicing process: recognizes specific rna sequences bracketing the introns. There are specific left and right boundary sequences. Works processively, first recognizes 5" boundary until it finds 3" boundary. Breaks of phosphodiester bonds holding intron to extron and creates new phosphodiester bonds to link the (now) adjacent exons. Alternative splicing: produces alternative mrna, more than one protein can be made from one gene.