PSL201Y1 Lecture Notes - Lecture 2: Oogenesis, Luteal Phase, Theca

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14 Dec 2011
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Reproduction l2; dec . 02, 11: female reproduction: more complicated in females since have to support baby. Female reproductive system: 2 ovaries hormone synthesis: estrogens, progesterone, inhibin; formation of gametes, oocyte ovulated into fallopian/uterine tube. Fertilized as develops goes to uterus embryo & fetus develops: no connection btwn reproductive & urinary tracts in females. Oogonia 2n, 46 chr, develop in fetus gonad that becomes female. Asymmetric cell division only one 2ndary oocyte (has most of cytoplasm) produced from each oogonium; 1 disintegrated polar body (has chr) Limited duration (no oocyte production after (don"t come from father sperm) menopause average age 51) ), might be possible to regenerate some primary oocytes w stem-like cells. Fecundity decreases after age 30: fecundity = ability to become pregnant, drops considerably after age 32, likelihood of healthy child drops even more, need hormone therapy to superovulate at age. Meiotic spindle becomes disorganized w age: rmbr oocytes in suspended animation/metaphase. Monthly cycle of adult women: ovarian cycle.

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