NFS382H1 Final: FINAL EXAM CHART
14 Dec 2011
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Document Summary
Use ais and 99% found in bones and teeth. Absorbed as hf by gastric mucosa (passive diffusion) Blood levels rapidly reflect dietary levels (not regulated) Has high affinity for osteoid proteins, so it may actually stimulate bone formation and form the center for mineralization. Excretion is 90% by kidneys, 10% in fecal loss, and very minor in sweat (iii) topical fluoride decreases acid production by oral plaque. Effects on growth, fertility, and anemia reported in animal models. Results from excessive exposure to fluoride from coal burning, industrial exposure, tea drinking or ground water that contains fluoride in excess of. Critical exposure is 1-4 years of age, over 8 years of age is not at risk. Crippling effects result from calcification of ligaments, muscle wasting and neurological defects. If discontinue fluoridation increase of 18-64% in dental carries. Cannot occur once tooth has erupted into oral cavity.
