PSYB65H3 Lecture : PSYB65 LECTURE 5
Document Summary
Hear people talking to them (delusions) affective disorders. ~ five genes involved in schizophrenia age of onset is prior than 30 yrs (early adulthood) Neuropsychological tests show poor performance on frontal lobe tasks show poor performance on verbal/nonverbal memory. Most neuropsychological tests show that they re completely normal (no tumour) enlarged ventricles and lighter brains. Meds are large tranquillers, unsure if it is genetic or medication. 10-15% of patients are also schizophrenic in family. Dizygotic twins (not identical) ratio of prevalence is around 10-15% that the other twin will be schizophrenic. Identical twins, the prevalence is 40-75% (environmental factors alter probability) 12 cases of twins; separated first yr of life (one twin has to be schizophrenic: 9/12 of schizophrenic (not purely genetic but predominant factor = genetic) Give schizophrenia this amphetamine , stimulate dopamine system. Typically, look at number of receptors, they have 6x of d4 receptor.
