Biochemistry 2288A Lecture : Cancer
2 Jan 2012
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Benign tumor (left): it s encapsulate and can be surgically removed (easily) Malignant tumor (right): these tumors are not contained (not encapsulated), so they can move throughout the body and tissue. It can start a benign but it can secrete proteases that allow it to go through the basal lamina and go into the blood stream where it can penetrate through blood vessels and metasise in other tissues. A very difficult form of cancer to treat. Normal tissue found growing on a basal lamina. Cancer cells can break through this lamina; no longer contained where they should be go into a lymphatic/blood vessel and spread throughout the body; or into other tissues and grow there. Some genes that result in cancer can be inherited. So we know cancer is a genetic disease because it can be inherited. If you inherit two bad copies of rb you get it at a young age. Chemicals that damage dna can result in cancer.
