HMB200H1 Lecture Notes - Pras, Myelin, Depolarization

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14 Jan 2012
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Quiz: 10 pages til 19th century, cajal vs. golgi; Why are neurons special: anatomy--processes and proteins. & ms (axons) ex. sensory toe medulla (longest) Making many prots, intracellular signaling prots much more common in ns: fast conduction of action potentials in. Many neurons don"t have act pots (ex. interneurons don"t need act pots, short distance: transmission--synapses, electrical (simple) & chemical (complex, involves 100s of prots). Localized, accumulation of (-)ions at surface, pull (+) ions towards works like 2 plate capacitor. Potentials: all potentials result from ions moving quickly across membranes, ex. Some can be prots (too big to move fast) Na move fastest to produce act pots. 2 forces on ions: chemical diffusion (like molec from high to low conc); electrical (attraction & repulsion): membranes can prevent movement & diffusion. Pumps exchange ions: all cells have pumps & resting pots (-40 to, na+/k+ pump: 3 na+ out, 2 k+ in.

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