PSYC 3250 Chapter Notes -Psychopharmacology, Reuptake
23 Jan 2012
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Pharmacokinetics is refered to the movement of a drug once it enters into the body, until the pt when it is excreted or metabolized. Intraperitoneal injection (ip): injected through the abdominal peritoneal cavity (space around the stomach, intestines and liver) [most common injection route for animals] Intrarectal administration: rarely used on animals, drugs must be in the form of suppositories (are mostly used when a drug can upset a persons stomach) Inactivation and excretion: enzymes found in the liver, blood and brain break down certain drugs, and the kidneys are able to absorb and excrete them. Sites of drug action: antagonists: are drugs that inhibit the postsynaptic effect, agonist: drugs which facilitate the postsynaptic effects to take place. Before a n. t creates its effects, it must be synthesized from its precursor/drug; sometimes the n. t release is increased (when the precursor acts as an agonist)
