MBG 1000 Lecture 7: MBG 1000- Lecture 7 notes

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periwinklewalrus158

23 Jan 2012

School

University of Guelph

Department

Molecular Biology and Genetics

Course

MBG 1000

Professor

Anne Lamontagne

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Document Summary

Birth defect: abnormal structure, function, or metabolism at birth (embryonic period- first 8 weeks) Problems of testing teratigenc drugs: effects pleiotropic: different in different people, animal testing often involves excessive doses, various species react differently, delayed reactions: cannot be detected at birth, drug synergism: 2 or more drugs simultaneously. German measles (rubella): cataracts, hearing, heart, diabetes. Herpes simplex virus: 40% of exposed acquire the virus (death, nervous system damage, skin sores) Spontaneous abortion (miscarriage): over 60% fertilized eggs (most have abnormal chromosomes) Age of onset: age of which symptoms begin to appear (early to middle adulthood) Alzheimer s disease (ad): less than 1% is inherited. Beta- amyloid: clump of proteins than form between the outside of the cells and the brain. Change in gene that encodes in a protein. Child usually dies at age of 15 from heart attack or stroke. Genes that protect from illnesses (heart disease, diabetes)

Related Questions

Which of the following is true about fetal alcohol syndrome? a. It is distinguished by rapid physical growth and facial abnormalities, but not cognitive impairment b. It is distinguished by slow physical growth, a pattern of facial abnormalities and brain injury c. It is extremely rare in the United States d. The mental impairment associated with it is temporary

Visit http://visembryo.com/baby/index.html and answer the following questions.

1. In embryo development stage 2, what type of replication are the first cells undergoing? What do you think would happen if a mutation occurred in one of these cells?

2. At about 16 days post-ovulation, what layer will give rise to the hair, nails, and skin?

3. Explain what a neural groove is, and at how many days post-ovulation does this form? What do you think might happen if this neural groove is not formed properly?

4. At what stage does the heart become a four-chambered heart? What do you think might occur if the heart does not completely differentiate into four different chambers?

5. During what stage is gender differentiated? What do you think might occur if the gender does not properly differentiate?

6. Describe two major developments that occur during stage 23.

7. During what week of development are the lungs completely capable of breathing air? Discuss genetic disorders involving the respiratory system?

8. Describe why an infant is born with 300 bones, while an adult has 206 bones. Discuss some birth defects that effect the skeletal system and identify if they are associated with a genetic condition.

9. Describe the development of the musculature in fetal development. Highlight any major genetic conditions involving the muscle system.

Human Embryo Development and Birth Defects adopted from: Kelly Day, CDCâs 2005 Science Ambassador Program

1) How do animals keep from digesting themselves?

2) What are the biological advantages of internal versus external fertilization and internal versus external development of the embryo?(internal/extrnal fertilization) and (internal/external develpment of embryo)

3) Why are eggs and sperm so different in size. What functions can you infer from their structure?

4) Why do humans crave fatty foods?

MBG 1000 Lecture 7: MBG 1000- Lecture 7 notes

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