BIO120H1 Lecture : Notes taken during lecture
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BIO120H1 Full Course Notes
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***read figure legends in textbook before class for next, next lecture*** vesicles move to plasma membrane to deliver cargo, including lipids: bring lipids from synthesis at er to golgi to vesicles. constitutive always on, always functional, default: if protein is synthesized into er lumen and has only er signal sequence, now soluble protein, it"s default fault is to be secreted in constitutive secretive pathway, be secreted. regulated e. g. insulin : those vesicles stay in cytosol, wait for signal. no sorting signal ends up in cytosol. so default pathway sentence should be changed for proteins with a er signal sequence and no other sorting signal . vesicles sitting under plasma membrane, waiting for signal. beta cells waiting under plasma membrane to release glucose. process of maturation depends on brining hydrolytic enzymes from. must have acid hydrolyase to be lysosome. phagocytosis www. notesolution. com: large vesicles that ingest large particles, microorganisms, dead cells .