BIOD27H3 Chapter 5: BGYB30 Chapter 5 textbook notes
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The law of mass balance: if the amount of a substance in the body is to remain constant, any gain must be offset by an equal loss. Total amount (or load) of substance x in the body = intake + production excretion metabolism. Mass balance = existing body load + intake or metabolic production excretion or metabolic removal. The rate at which a molecule disappears from the body by excretion, metabolism, or both is called the molecule"s clearance. Mass flow (amount x/min) = concentration (amount x/vol) volume flow (vol/min) At the same time, however, the body is in a state of chemical disequilibrium, in which the major solutes are more concentrated in one of the two body compartments than in the other. > whereas, k + are more concentrated inside the cell. > ca2+ is more concentrated in the extracelullar fluid than in the cytosol, although many cells store ca2+ inside organelles such as the endoplasmic reticulum and mitochondria.
