BIO130H1 Lecture 4: Second Half Lecture 4.doc

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peachzebra67

26 Mar 2012

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Document Summary

Transport of glucose from intestine to blood stream. Terminology: glucose movement: intestinal lumen intestinal epithelium extracellular fluid, glucose concentrations: intestinal lumen (l), intestinal epithelium (h), extracellular fluid (l) The transition requires going through a connecting cell attached to intestine outside: apical domain of cell faces intestinal lumen, basal domain of cell faces extracellular fluid. Lateral domain of cell faces intestinal epithelium: basal + lateral = basal-lateral domain. Tight junctions prevent movement of material between adjacent cells. Important towards resting membrane potential: osmotic balance. F-type: use h+ gradient to produce atp. V-type atpase: h+ pump, opposite of f-type, use atp to pump h+ into organelles against gradient, acidify lumen. Abc transporters: abc = atp binding cassette. Pump small molecules, ex. various toxins, drugs: small molecules general not charged. Passive transport: channel is opening to allow passive passage, faster than transporters. Membrane potential: outside the cell includes na+/cl- ions.

Related Questions

1. When gram-postive bacteria and red blood cells are placed inhypotonic media, what would happen to these cells? Identify themolecule that passes across the plasma membrane, and the directionof the movement of this molecule. 2.Explain the mechanism by which intestinal epithelial cellsefficiently trap glucose from intestinal lumen and supply it to thebody fluid. Include all membrane proteins, driving force to moveglucose across each membrane, and any structures that help theprocess.