BIO130H1 Lecture : Second Section Lecture 5

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26 Mar 2012

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Cytosol: half of cell volume, degradation and synthesis of proteins, small molecules for metabolism, not an organelle. Organelles: subcellular component with distinct function, usually membrane enclosed. Lysosome/vacuole (in plants): digestive enzyme: golgi apparatus: modifies proteins and lipids, mitochondrion: used for atp synthesis, nucleus: dna/rna synthesis, rer (rough endoplasmic reticulum): synthesis of various proteins, ser (smooth): phospholipid synthesis, detoxification. Endosome: endocytosis, absorbs other molecules by engulfing them. Endomembrane system: composed of endosome, peroxisome, ers, golgi apparatus, lysosome/vacuole. Involved in two main pathways: biosynthetic/secretory pathway, proteins and lipid made in er (biosynthesis, delivered to other organelles (bio, helps secreted proteins move out of the cell through exocytosis (secretion, endocytic pathway. 15/12: move contents into cell through endocytosis. Vesicle: membrane-enclosed organelle that transports components in endomembrane system. Exocytosis: transported vesicle content delivered to extracellular space, vesicle membrane fused with cell plasma membrane, secretion. Endocytosis: cell plasma membrane forms vesicle membrane, vesicle contents come from extracellular space, engulfing.

Related Questions

(a) Mitochondria (b) Endoplasmic reticulum (c) Nucleus (d) Lysosome (e) Endosome (f) Peroxisome (g) Golgi apparatus

_____ quality control of mRNA

_____ location of oxidative phosphorylation

_____ responsible for detoxifying organic molecules (liver cells)

_____ houses and protects genetic material

_____ responsible for modification and sorting of proteins and lipids

_____ location of ATP synthesis

_____ responsible for sorting endocytosed materials

_____ site of degradation and digestion

_____ responsible for oxidizing toxic molecules

_____ location of lipid synthesis

_____ location of hormone synthesis (adrenal cells)

B. Which organelle(s) from the above list communicate(s) with other organelle(s) through the use of vesicular transport? ________________

C. Which organelle(s) from the above list receive proteins made in the cytosol?___________________

D. Through which organelle(s) must proteins pass to reach the organelle(s) which do not receive proteins made exclusively in the cytosol?______________

E. Entrance into which organelle(s) requires that proteins unfold and snake through the membrane? _________________

F. How do organelles maintain their position in the cytosol? Be specific.

G. Give 2 advantages that eukaryotic cells gain by having organelles.

tealtoad562

Please match the following:Nucleus, cytoplasm, plasma membrane, ribosome, rough endoplasmic reticulum, smooth endoplasmic reticulum, golgi apparatus, vesicles, lysosomes, central vacuole, mitochondrion, chloroplast, cell wall, cytoskeleton, gap junction, tight junction, plasmodesmataA. Structure between cells that forms leak proof sheetB. Stacks of membrane sacs that receive and modify protein products coming from the rERC. Fluid-Filled space between the plasma membrane and the nuclear membrane where organelles are suspendedD. Supports cell, maintains cell shape, acts as tracks for organelle movementE. Cellular respiration, bulk of ATP productionF. Outer border of plant cellsG. Storage, digestion, maintains, turgor pressure in plantsH. Genetic control center, directs cellular activitesI. Selective barrier of all cellsJ. Converts solar energy to chemical energyK. Structure that allows substances to flow from one cell to another cellL. protein factoryM. digestive compartment in animal cellsN. synthesis, modification, and packaging of proteinsO. transport shuttle busesP. stacks of tubules where carbohydrate and lipid are producedQ. Channels connecting neighboring plant cells

brownwoodchuck820

You study a transmembrane protein that is trafficked through theendoplasmic reticulum but ultimately âlivesâ in the plasmamembrane. Suppose the domain of this protein which is exposed onthe outer face of the endoplasmic reticulum membrane was covalently(and specifically) labeled with a fluorescent dye in a living cell.When the protein is distributed among cellular compartments, wherewould you expect the dye to be located?

Question 7 options:

A) The dye will be on the outer face of the endoplasmicreticulum, on the inner face of the Golgi apparatus, and on theextracellular face of the plasma membrane.

B) The dye will be on the inner face of the endoplasmicreticulum, on the inner face of the Golgi apparatus, and on theintracellular face of the plasma membrane.

C) The dye will be on the outer face of the endoplasmicreticulum, on the outer face of the Golgi apparatus, and on theintracellular face of the plasma membrane.

D) The dye will be on the outer face of the endoplasmicreticulum, on the outer face of the Golgi apparatus, and on theextracellular face of the plasma membrane.

Eukaryotic cells manufacture fibrous cytoskeletal proteins thatfunction in the cytoplasm to maintain cell shape by providingstructural support, move materials within the cell, and move theentire structure. Which of the following predictions about proteinsynthesis, processing, and trafficking applies to the general classof cytoskeletal proteins?

Question 8 options:

A)	They would be glycosylated in the Golgi apparatus.

B)	They might travel to the nucleus in a transport vesicle with aspecific zip code.

C)	They would initially contain signal sequences that would allowtheir entrance into the endoplasmic reticulum.

D)	They would be manufactured on free ribosomes in thecytoplasm.

turquoisecoyote785

BIO130H1 Lecture : Second Section Lecture 5

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