BIOL 200 Lecture Notes - Homologous Recombination, Amphoterism, Chromosome
6 Apr 2012
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Document Summary
Genomics allows us to do this, by studying the genome as a whole. Genomics has four particular uses: finding out gene structure, finding out gene function, looking for evolutionary relationships, such as where divergences take place. Take this hybridized microarray: the colors have been assigned so that green means the gene is expressed more in condition a, red means higher expression in condition b, and yellow means unchanged expression. Mcgill fall 2011: rna samples of different origin can be monitored on the same microarray if the two samples are labelled with different fluorescent dyes. You will be able to tell which gene it is because you have recorded which oligonucleotide was placed in this well. In this example, green light means this gene was downregulated during cell division, red means it was unregulated, and yellow means it was unchanged: this gives an idea of the overall gene expression during cell division.
