NUTR 1010 Lecture Notes - Heme, Myelin, Cysteine

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Rda for men and women >19 y is 400 g/d. Folic acid is the active form of folate. Naturally-occurring food folate converted to folic acid in the body. We also consume folic acid: in supplements, in fortified foods (e. g. grain products) We absorb almost 100% of folic acid, but only ~50% folate. Functions of folic acid (active form of folate) Plays a role in dna synthesis: important in new cell and tissue formation, critical during first few weeks of pregnancy. With vitamin b6 and b12, maintains normal homocysteine levels: homocysteine: amino acid with increases blood coagulation and ldl oxidation, ~10% of risk of developing cardio vascular disease due too hyperhomocysteinemia. No problems w/ consuming too much folate (naturally-occurring form) Too much folic acid can mask vitamin b12 deficiency [more on this next class: because of this, upper level for folic acid= 1000 g/day.

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