HLTC23H3 Lecture 10: HLTB02 lecture 10.docx

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12 Apr 2012
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Most kids are not dying from aids-2% mortality (social factors, human factors, easily mediated, social stigma) Death due to opportunistic infections (hiv causes body unable to fight back), children are already underdeveloped, hiv affects it even more. Transfer to children: vertical transmission (breast feed, pregnancy), blood transfusion, drug, sexual transmission (unprotected sex, raped) Children are more affected than adults, progression is faster than adults, opportunistic infections (pneumonia, ear infections, tb, etc. ) Relationship between tb and hiv- double trouble ; hiv increase susceptibility to. Tb, reactivate latent tb, acceleration of active tb, resistant to anti-biotic treatment. Greater expo to tb-co-infected, drug resistant, mortality rate, problem=screening. High tb, less control, co-infection-sub saharan (south) africa, poverty, structural factors involved. Reasons for tb/hiv: higher expo and higher vulnerability. Treatment: anti-retrovirals (slow progression of hiv-haart), screening for tb (tst) Anti-retroviral: slow down progression, reduce mortality, different classes of drugs, best one is haart, expensive though (patent costs, generic would b cheaper, pharmaceutical industries)

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