BIOL 112 Lecture Notes - Glycerol, Pyruvic Acid, Mitochondrion

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BIOL 112 Full Course Notes
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BIOL 112 Full Course Notes
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Citric acid cycle: complete oxidation of acetyl-co a (c2, thus, 2 co2 are released, the enzymes dehydrogenase, are coupled with the oxidation of the molecules through nad+/fad+ which results in the loss of a co2 and/or creating. Fadh2/nadh+h: 3 nadh+h+, 1 fadh2, 1 atp and 2 co2 are produced. Uses nadh+h+ and fadh2 generated to create atp. Flow of electrons in a series of redox reactions causes active transport of protons across inner mitochondrial membrane. Potons then diffuse down gradient into matrix, and this causes creation of atp. Etc consists of 3 large protein complexes bound to inner mitochondrial membrane and cytochrome c and ubiquinone which are hydrophobic carriers that shuttle hydrogens/electrons from one complex to the next. Note: fadh2 couldn"t produce enough energy for the redox of the first complex in the chain even if it could bind. Each redox reaction results in a conformation of the complexes, causing/generating a channel to move the hydrogen.

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