PSYC55H3 Lecture Notes - Frontal Lobe, Brodmann Area 46, Electrophysiology

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20 Apr 2012
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Search task- every single well has food under- monkey uncover the well and take food-if the monkey returns to the wall that they have already been to- if its empty counted as an error. Increase the number of trials-monkeys with lesions to sulcus principals and superior pfc do worse on the task. Area 46 is important in monkey has to hold info in short term memory. Electrophysiology- delay response task-give cue, delay, and go period. Sulcus principal- fires the most during the delay period. Monkeys fixate on the centre of the screen- square flash off somewhere on the screen, delay phase which cue disappears, response phase- make a response to where the cue will appear or to the opposite side. Dorsalateral prefrontal cortex- cell fire significantly during the delay period. During the error period- activity low compare to if they get it right. Goldman rakic- prefrontal cortex is responsible for the temporary maintenance of memory.

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