HMB265H1 Lecture : Notes taken during lecture

64 views4 pages
29 Mar 2011
School
Department
Course
avalack09 and 39844 others unlocked
HMB265H1 Full Course Notes
25
HMB265H1 Full Course Notes
Verified Note
25 documents

Document Summary

Effects of diet, x chromosome inactivation, and parental imprinting. Even with monozygotic twins, there are still subtle differences: differences may become more apparent as they age, especially in terms of health. heritable modifications/changes in gene function not due to changes in underlying baseline. changes in gene expression created by: dna methylation. results in repression of gene expression: covalent modification of histone. lead to repression or activation of transcription: recruitment of chromatin modelling complexes or specific variants of histones, non-coding rnas. Epigenetic and these mechanisms cause coat colour differences btw mice: agouti gene is pleiotrophic gene. Implicated in many traits, including coat colour, viability, obesity. Fat mice also prone to diabetes and cancer. retrotransposon inserted upstream of normal wildtype agouti promoter: retrotransposon has inserted its own cryptic promoter, mice with viable yellow alleles have constant expression of this.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents

Related Questions