IMM250H1 Lecture : Notes taken during lecture
Document Summary
Final exam multiple choice covering everything taught in lecture april 28th. Inflammatory response local t ries to contain infection from where organism t rying to enter. Hygiene hypothesis society is too clean thus asthma, etc. developing. sepsis: aka sirs, response is inflammatory, innate immunity typically local. Inflammation occurs restricted to that site of infection. contained: in sepsis, all cells in body react to bacterial products, producing cytokines and inflammatory mediators. thus massive inflammation at whole body level. victims often children, immunocompromised individuals, elderly: their immune systems not as effective as healthy adults, mortality rate is approx 50, ex. Incidence of sepsis versus more popular killers: sepsis has higher incidence, also for mortality, neck to neck with heart attacks. sars: coronovirus virus resembles crown, pandemic defined as spread of infectious disease worldwide, caused major problems, spread within a matter of weeks. reservoir thought to be bats do not have overt disease symptoms.
