NUTR 3210 Study Guide - Vitamin B6, Methyl Group, Aldehyde
16 May 2012
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Micronutrients 3: micronutrients that act as enzyme cofactors: non protein that is needed for the enzyme to function. Co-enzymes: moves around in solution, acts as a substrate. Adp ribose: deficiency disease is pellagra; (dermatitis, dementia, diarrhea, death) epidemics historically due to dependence on corn as dietary staple. Fad that is tightly bound to the glutathione reductase enzyme. Fad 3 fadh2 and passes these two electrons to gssg: fad is the prosthetic group for. Gssg: there is no clear deficiency disease, but if dietary intake is inadequate general symptoms will be observed, with the most distinctive being related to the mouth (cracks, inflammation) Pantothenic acid (pa: pa is plant provitamin, 4-phosphopantethiene is active form in fatty acid synthesis, coa (coash) is active form in catabolic reactions, no deficiency disease as widely distributed. Biotin: no plant provitamin, just functions as biotin, biotin acts as a cofactor for: (1) pyruvate carboxylase (2) acetyl coa carboxylase (3) propionyl.
