ANAT 262 Lecture Notes - Syntaxin, Cryogenic Transmission Electron Microscopy, Phagocytosis

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The secretory pathway is made of the er, golgi, endosomes and lysosomes, while the endocytic pathway is made from the pm, endosomes, golgi and lysosomes. From the inside out, the secretory pathway contains: the er, pre-golgi intermediates, also called intermediate compartments or vtcs, the golgi, post-golgi carriers (several kinds) and secretory vesicles, the cell surface and cell exterior. The endocytic pathway is made of, from the outside in (oversimplified, but all we need to know for now: the pm, early endosomes (though alternate pathways exist, late endosomes, lysosomes, which are degrading organelles. Also, direct pathways between golgi and endosomes create a linkage between the secretory and endocytic pathways. Keith portman first discovered the er in 1945 through obtaining some crude em pictures stained with carbon (not a quality image in today"s standards) Proper staining techniques really began to shape in the.

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