HLTB21H3 Lecture Notes - Leprosy, Miasma Theory, Industrial Revolution
Document Summary
Type: water or food borne disease, sewage disease. History: the finding of germ theory, microscopes, salt water therapy, rehydration (latta), results in sanitary reforms and improvement of health systems, has also used to scapegoat those suspected of being carriers, 7 pandemics still occurring today. Symptoms: causes severe diarrhea producing rice water stools, vomiting, convulsions, muscle cramps, but little abdominal pain, leads to loss of water and electrolytes but not protein, radical dehydration, ruptured capillaries causing them to be black and blue. Death: rice water stools, severe dehydration in less than 10%, sometimes within hours. Vaccines: partial immunity can be acquired from previous infections. Control/prevention: sanitation, proper disposal of wastes, water purify, surveillance. Genus: vibrio cholera, gram negative, comma shaped bacillus (koch during 5th epidemic 1882) Has two viruses within it, one that codes for cholera toxin, the other codes for the receptor which allows the toxin coding to enter bacterium.
