HLTB21H3 Lecture Notes - Fritz Schaudinn, Arsphenamine, Headache

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2 Jun 2012
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Poem about a shepherd boy named syphilis who insulted a god and was punished by that god with the disease. Theories: introduced to europe from the new world columbian theory. The pattern of spread of the disease: pre-columbian/ anti-columbian theory. Nonunitarian mutational changes in the treponemal strains themselves. Many populations of native americans themselves were decimated by syphilis in the 16th century after the arrival of the europeans. Developed the signs of syphilis and concluded the two infections were the same. Eventually died of heart problem tertiary syphilis. Demonstrated that gonorrhea and syphilis were different diseases. Determined the 3 stages primary, secondary and tertiary. Established that syphilis was spread through the body by the blood. 1905 shaudinn and hoffman discovered the germ that causes syphilis. They had syphilis but were told they had bad blood . Extremely fragile spirochete surviving only briefly outside the host.

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