NUR1 324 Lecture Notes - Renin, Osteoporosis, Follicular Antrum
Document Summary
Involves hormone secretion into the blood by endocrine gland. To hormone is transported by the blood to a distant target site. Example of long-distant signalling: the anterior pituitary gland releases lh and fsh which are transported to the gonads (target site) through the blood vessels. The gonads then release steroid hormones (estrogens in females and androgens in males) These travel to a non-neuronal tissue and elicit hormonal response. Paracrine signalling: ex: parathyroid hormone related peptide is a paracrine signalling hormone, ex: cancer cells release factors that tell the cells to divide. They are absolutely necessary for proper communication to occur: certain dietary substances also function as hormonal signalling molecules. Gonads: ovaries in female, testis in male. Via blood vessels of the pituitary stalk. Hypothalamic-hypohyseal portal system: from the hypothalamus to the adenohypohysis. Hypothalamic neurohormones act on one of the six types of hormone-producing cells in the anterior pituitary. Tells nothing about physiology and receptors (except for steroids)
