ANTC41H3 Chapter Notes -Thrifty Gene Hypothesis, Insulin Resistance, Dietary Fiber
30 Jun 2012
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Aims to reduce body weight, improve insulin resistance, and modify cv risk factors. Cvd, diabetes and cancer, diet, insulin resistance and diabetes: the right (pro)portions spence, mckinley and. Diet and lifestyle mod are the cornerstone of prevention of type 2 diabetes. Idea that overconsumption leads to weight gain has been around since 460 bc. Hyperglycaemia and abnormal glucose metabolism is the defining feature of diabetes and there is still a widely held belief that a high intake of sugar is a particular risk factor. It is now est that excess fat intake and disturbances in fat metabolism are associated with insulin resistance and diabetes. Concept of insulin resistance emerged following discovery of insulin. Insulin sensitive = type 1, insulin resistant = type 2. Early experiments investigated the effect of altering relative amounts of carbs and fat on insulin action showing that blood glucose lowering effect of insulin is enhanced as carbs increase.
