CSB328H1 Study Guide - Midterm Guide: Dishevelled, Cyclin-Dependent Kinase 1, Pronucleus
7 Sep 2012
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Fertilization: sperm binds to jelly layer. Egg releases ligand from vitelline envelope or jelly layer. Sperm receives ligand by receptors on head. Acrosome releases enzymes into jelly layer by exocytosis: sperm cell membrane binds to egg cell membrane. Sperm sends acrosomal process (actin) towards vitelline envelope. Bindin on acrosomal process binds to bindin receptors on vitelline envelope and breaks down vitelline envelope. Egg membrane and sperm membrane fuse: sperm haploid nucleus and centriole enter egg. Centriole rotates 180 degrees: female pronucleus and male pronucleus fuse. Centriole sends out microtubules toward the egg nucleus. Female pronucleus and male pronucleus become diploid nucleus. Centriole duplicate and position at opposite poles of the egg cell. Cell division by mitosis: fast block (transient; 1 minute) Influx of na+ ions into egg: slow block (permanent, physical) Wave of ca2+ release into cytoplasm around the egg. Release glycoproteins into space between vitelline envelope and cell membrane.
