BMSC 230 Lecture Notes - Glyceraldehyde, Reversible Reaction, Ketose
12 Oct 2012
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Non-phosphorylated molecules can be transported across the membrane. Negatively charged and impermeable across membrane: stay inside cell. Synthesis of atp: transfer phosphate group to adp to produce atp. Provide proper fit for binding between substrate and enzyme. Pathway provides 2 + 5 = 7 atp. If pathway has to operate under standard conditions it cannot proceed because 4 values are positive. Actual free energy change is considered and not standard free energy change. Can have one positive number in actual free energy change. Energy starts from a high point and slowly decreases. Shown with actual free energy change graph. Yeast doesn"t have the enzyme to convert pyruvate to lactate. Pyruvate converted to ethanol + co2 instead. Capacity to drink alcohol is directly related to the amount of alcohol dehydrogenase in the liver. More alcohol dehydrogenase = able to consume more alcohol. Alcohol dehydrogenase slowly increases when alcohol consumption is high. Co2 doesn"t exist as co2 in living systems.
