CHMB42H3 Chapter Notes - Chapter 21: Amine, Ammonium Hydroxide, Reagent

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18 Oct 2012
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Chapter 21: more about amines heterocyclic compounds. Amines compounds in which one or more of the hydrogens of ammonia (nh3) have been replaced by an alkyl group. The lone-pair electros of the nitrogen atom cause amines to react as bases, sharing the lone pair with a proton, and as nucleophiles, sharing the lone pair with an atom other than a proton. Some amines are heterocyclic compounds (or heterocycles) cyclic compounds in which one or more of the atoms of the ring are heteroatoms. 21. 1 more about the acid-base properties of amines. 21. 3 amines react as bases and as nucleophiles. The lone pair on the nitrogen of an amine causes it to be nucleophilic as well as basic. 10. 8 amines do not undergo substitution or elimination reactions. The weaker the acid, the stronger its conjugate base and the poorer the base is as a leaving group.

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