PSYC62H3 Chapter Notes - Chapter 5: Rimonabant, Inverse Agonist, Monoamine Oxidase B
Document Summary
Include classic transmitters i. e. glu, gaba, ach, da, ne, s-ht + newly characterized substances i. e. Include classic transmitters i. e. glu, gaba, ach, da, ne, s-ht + newly characterized substances i. e. anandamide. Chapter 5: synaptic transmission, drugs & chemical neuroantomy. Neurotransmitters & chemical signalling in the nervous system. Neurotransmitters commonly viewed as chemicals located in specific regions of neurons, released under specific stimulation, act on specific set of receptors & induce some type of postsynaptic action i. e. change in membrane potential or metabolic activity (an) & adenosine. Neurohormone: substances that are synthesized & released from neurons but act as hormones i. e. corticotrophin releasing factor released from hypothalamic neurons & acts at anterior pituitary gland. Neuromodulator: any substance that alters neurotransmission in some way. Doesn"t show any direct shifts in membrane potential/conductance. Same substance can meet definition of neurohormone, neuromodulator & neurotransmitter i. e. da. Most substances that are neurotransmitters also act as neuromodulators.
