BCHM 2021 Lecture Notes - Lecture 16: Geminin, Ubiquitin Ligase, Cdk Inhibitor

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21 Oct 2012
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Cell cycle cycle of cell growth and division he chromosome. Replicate the organelles grow and duplicate these have to get segregated to the daughter cells. Increase in mass so that the cells are coordinated with the division. If we don"t want the cells to get smaller and smaller. Time for growth and monitor environment see if conditions are favourable to go ahead. The cell cycle = g1 s g2 m g1. G1 + s + g2 = interphase and then you have mitosis. These principles are similar in all eukaryotes similar proteins found in all organisms. Some of the genes comes from the yeast mutants cdc mutant cell division cycle . Question: the budding yeast and the fission yeast are sued to study many cellular processes because of their genetics. Most conditional cell-cycle mutants are temperature sensitive; the mutant protein fails to function at high temperature, but performs well enough at low temperature to allow cell division.

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