BIO270H1 Lecture Notes - Lecture 3: Integral Membrane Protein, Peripheral Membrane Protein, Active Transport
Document Summary
Cellular membrane: selectively permeable membrane with 2 primary functions, 1. Temperature and membrane fluidity: environmental conditions, high temperature: phospholipids are far apart, low temperature: phospholipids are close together. Membrane protein: integral membrane protein: tightly bound; embedded in membrane, peripheral membrane protein: integral membrane proteins of glycolipids. Ion channels: small pores for specific ions, open and close and. Permeases: limit molecules and changes conformation: ion channels. Mechanogated: responses to the movement in the cell: active transport. P-pump: pump specific ions (na+, k+ and ca2+) Antiport/ exchanger: move molecules in different directions. Electrical gradients: all chemical gradients, electroneutral carriers: transport neutral molecules/exchange in an equal number of molecules, electrogenic carriers: unequal charge. Membrane potential: resting membrane potential (vm) Difference inside and outside the cell membrane: two primary functions. Cellular structure: eukaryotic cells share many common cellular compartments. Mitochondria: powerhouse of the cell, large interconnected membrane, has mtdna. Cytoskeleton: microfilaments: flexible chains of actin, microtubules: tubes of tubulin, intermediate filaments: many monomers.
