PSYB65H3 Lecture Notes - Lecture 6: Monoamine Oxidase, Dopamine Receptor, Tricyclic Antidepressant
Document Summary
Most patients have auditory hallucinations ppl talking to them, and delusions ppl plotting against them. Recent findings show that sch and affective (emotional) disorder like depression share the same genes. Age of onset prior to 30, usually early adulthood. Poor performance in frontal lobe tasks; tests of frontal lobe function. => issues in the frontal lobes, studies aren"t 100% conclusive. Poor performance on tests of verbal and nonverbal memory. Most other neuropsych tests show completely normal. Most patients have enlarged ventricles and lighter brains. => may be due to the prescribed tranquilizers that patients have to take for many years. Hard to determine what effects are caused by the actual disease, and what effects are caused due to side effects of the medication. 1% of population develops sch, in immediate family 10-15% will develop if a relative has it (parents, children, siblings)