Biology 1001A Lecture Notes - Lecture 8: Transposase, Retrovirus, Antimicrobial Resistance
19 Nov 2012
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Lecture 8 outcomes: different types of genomic variation among humans. 300 variants in insertion of retro elements (lines, sines) Meiosis: structure of is elements, transposons, retrotransposons and retroviruses. Insertion sequence seqence of genes codes for its own mobility, codes for trans- posase. Transposase is a recombinase, makes cuts in dna backbones. Moves the is into a different site. So is codes for its own mobility transposons is the dna that gets transposed. Carry genes for things like antibiotic resistance. A problem since they can move around in bacteria retrotransposons. Moves from one place to another by reverse transcribing their genes into double stranded dna and inserts that copy to another place. That retrovirus got a mutation so that it can"t out of the cell. Therefore it gets stuck in your genome 45% These can cause diseases because it messes with the genome. But probably not cause of chronic diseases.
