BIOL 102 Lecture Notes - Schwann Cell, Macrophage
Document Summary
Using proteomics to resolve the phenotype of olfactory ennsheathing cells. 1000 new cases of spinal cord injury every year; predominantly men. Approximately 45000 canadians who are living with spinal cord injuries (i. e. rick. Spinal cord injury trauma results in damage to descending (motor) and ascending (sensory) axons, as well as autonomic axons that control urinary bladder and bowel function. Trauma also results in damage to bbb, resulting in the infiltration of inflammatory cells, which further exacerbates local injury. At site of injury, cystic cavity forms where there is a loss of spinal neurons, axons, and other glial support cells. Cavity is surrounded by a thin layer of spared axons. Marrow stromal cells & activated macrophages from bone/blood. Oecs surround olfactory axons as they extend from . Oecs and schwann cells (scs) are strikingly similar cells.