OC2255952

University of Massachusetts - Boston

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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 34: Somatic Cell Nuclear Transfer, Hematopoietic Stem Cell, Stem-Cell Niche

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18 May 2018
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Tissues comprised several different specialized cell types. Different cells have to be produced in correct numbers and have to reside in appropriate sp
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 33: Basal Lamina, Ultimate Tensile Strength, Intermediate Filament

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18 May 2018
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Cells w/in tissue often specialized to perform a particular function. Cells joined to one another w/o gaps. Cell-cell connections allow cells withstand
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 32: Mitochondrion, Fas Ligand, Cytochrome C

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18 May 2018
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Plasma membrane integrity is preserved (until later stages) Depolarization and permeabilization of mitochondria; release of cytochrome c. Disassembly o
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 31: Spindle Apparatus, Actomyosin Ring, Sister Chromatids

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18 May 2018
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Chromosomes aligned at equator of spindle, midway between spindle poles. Kinetochore microtubules on each sister chromatid attach to opposite poles of
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 30: Spindle Apparatus, Sister Chromatids, Actomyosin Ring

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18 May 2018
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G1, s, g2 phases make up interphase. Dna of chromosomes is replicated, centrosome is duplicated. Changes in cytoskeleton in preparation for mitosis. Se
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 29: Origin Recognition Complex, Cdc6, Spindle Apparatus

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18 May 2018
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Involves duplication and division of cellular material: 1: cell growth and chromosome duplication, 2: chromosome segregation, 3: cell division. Complet
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 28: Sliding Filament Theory, Endoplasmic Reticulum, Atp Hydrolysis

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18 May 2018
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Lecture 28 notes: contractile ring in cell division, contractile bundles (cell shape change, microvilli (diff from cilia, lamellipodia and filopodia in
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 27: Situs Inversus, Coiled Coil, Intermediate Filament

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18 May 2018
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Cells have filamentous structures inside them that help maintain cell shape and organization. A protein network of filaments that extends throughout th
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 26: Mitogen-Activated Protein Kinase Kinase, Protein Kinase, Lipid-Anchored Protein

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18 May 2018
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Activation of rtk stimulates assembly or intracellular signaling complex. Activated intracellular kinase region in one receptor molecule phosphorylates
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 25: Adenylyl Cyclase, Small Gtpase, Molecular Switch

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18 May 2018
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Largest family of cell surface receptors, more than 800 diff gpcr"s in humans. Used in visual system, olfaction, neurotransmission, many other function
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 24: Protein Kinase, Autocrine Signalling, Nuclear Receptor

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18 May 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Chapter Notes - Chapter 20: Adherens Junction, Basal Lamina, Cell Junction

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17 May 2018
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Chapter 20: cell communities: tissues, stem cells, and cancer. Cell junction that helps hold together epithelial cells in a sheet of epithelium; Descri
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Chapter Notes - Chapter 19: Homologous Chromosome, Homologous Recombination, Sister Chromatids

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17 May 2018
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Chapter 19: sexual reproduction and the power of genetics. An alternative form of a gene; for a given gene, many alleles may exist in the gene pool of
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Chapter Notes - Chapter 18: Spindle Apparatus, Cdk Inhibitor, Programmed Cell Death

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2 May 2018
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Stage of mitosis during which the two sets of chromosomes separate and are pulled toward opposite ends of the dividing cell. Protein complex that trigg
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UMASS BOSTONEHS 150Ivanov MilkoSpring

EHS 150 Study Guide - Midterm Guide: Breakfast Cereal, Vitamin B6, Vitamin K

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29 Apr 2018
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To improve his overall strength, anthony has been weight lifting in addition to running. He is now focusing on the nutrient mix of his post-weight lift
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Chapter Notes - Chapter 16: Extracellular Fluid, Artificial Cardiac Pacemaker, Skeletal Muscle

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20 Apr 2018
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Adjustment of sensitivity following repeated stimulation; allows a cell or organism to register small changes in a signal despite a high background lev
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Chapter Notes - Chapter 17: Molecular Switch, Epidermolysis Bullosa, Filopodia

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20 Apr 2018
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Protein that interacts with actin monomers or filaments to control the assembly, structure, and behavior of actin filaments and networks. Thin, flexibl
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 23: Lipid Bilayer Fusion, Cell Membrane, Electron Microscope

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5 Apr 2018
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Integral membrane proteins (transmembrane, monolayer-associated helix, lipid-linked) or peripheral membrane proteins (protein attached) Endocytosis: fr
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 22: Nuclear Pore, Chloroplast Dna, Nuclear Membrane

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5 Apr 2018
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Membrane-enclosed structures that contain a specific set of proteins and are specialized to perform different cellular functions. Homogenization in a b
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 21: Photosystem I, Atp Synthase, Electrochemical Gradient

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5 Apr 2018
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Chloroplast: takes in light, water, co2, to produce o2 to create sugar, sugar is taken in by mitochondria along with o2 to produce co2 and atp. Chlorop
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 20: Nadh Dehydrogenase, Lactate Dehydrogenase, Atp Synthase

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5 Apr 2018
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Conversion pyruvate to lactate (fermentation) yields no more atp and is used to regenerate. Nad+ plus lactate dehydrogenase leads to lactate. Glucose +
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 19: Acetyl-Coa, Citric Acid Cycle, Metabolic Pathway

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5 Apr 2018
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Occurs in stepwise fashion, allows for capturing some of released energy as opposed to releasing energy all at once and losing it as heat. Comes in for
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 18: Neurotransmitter Receptor, Cell Membrane, Membrane Potential

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5 Apr 2018
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Axons terminate on other neurons or other cell types. Depolarization of plasma membrane in neuron trigger action potential (nerve impulse) Action poten
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 17: Electrochemical Gradient, Resting Potential, Potassium Channel

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5 Apr 2018
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In all cases, energy input needed to drive energetically unfavorable process. Na+ pump moves na+ out of cell and k+ in, against their electrochemical g
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 16: Lipid Bilayer, Adenylyl Cyclase, Lipid Raft

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 15: Lipid Bilayer, Membrane Lipids, Cell Membrane

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5 Apr 2018
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Membrane enclose compartments and act as selective barriers for molecules. Maintain cell integrity and prevent mixing of components primary functions.
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 14: Polymerase Chain Reaction, Human Genome Project, Celera Corporation

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5 Apr 2018
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Used to generate large amount of particular dna. Primers used in excess to allow for short annealing times, added to 3" ends. Dna double stands heated
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 13: Dna Ligase, Restriction Enzyme, Nucleic Acid Hybridization

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5 Apr 2018
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Isolating a gene from a chromosome: generating new (recombinant) dna molecules in a test tube. Introducing recombinant dna molecules back into a living
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 12: Lac Repressor, Lac Operon, Catabolite Activator Protein

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 11: Release Factor, Reading Frame, Transfer Rna

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 10: Small Interfering Rna, Messenger Rna, Rna Splicing

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 9: Differential Centrifugation, Okazaki Fragments, Dna Ligase

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 8: Spindle Apparatus, Dna Replication, Nucleic Acid Double Helix

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 7: Sodium Dodecyl Sulfate, Polyacrylamide Gel Electrophoresis, Allosteric Regulation

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 6: Nuclear Magnetic Resonance, Circular Dichroism, X-Ray Crystallography

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 5: Atp Hydrolysis, Hydrolysis, Metabolic Pathway

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 4: Chemical Polarity, Dna Ligase, Activation Energy

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5 Apr 2018
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Energy flow: energy released from food is harnessed b cells in useful form, food broken down in useful forms is less disorder than the actual food part
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 3: Van Der Waals Radius, Rudolf Virchow, Ultracentrifuge

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5 Apr 2018
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Cell theory: all life forms made from one or more cells, cell is smallest form of life (rudolf virchow, every cell originates from pre-existing cell. S
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 2: Green Fluorescent Protein, Scanning Electron Microscope, Roger Y. Tsien

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5 Apr 2018
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UMASS BOSTONBIOL 212alexey veraskaSpring

BIOL 212 Lecture Notes - Lecture 1: Homeostasis, Zebrafish

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5 Apr 2018
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Diseases happen when cells malfunction, so understanding how cells normally work vs. what happens in a diseased cell helps us design therapies and drug
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