Pharmacology 4350A/B Study Guide - Panitumumab, Cetuximab, Cyp2B6

Allele - specific sequence variation of a gene. Haplotype - chromosomal region which groups of alleles are more frequently inherited together. Thiopuri

Pharmacology 4350A/B Study Guide - Cyp3A5, Cytochrome P450, Sulfamethoxazole

Slow body growth but rapid psycho/social growth + fine motor. Extracellular water decrease + intracellular water increase as you age. Liver + kidney la

Pharmacology 4350A/B Lecture Notes - Lecture 10: Torcetrapib, Pioglitazone, Atorvastatin

Rosiglitazone increase vascular events + pioglitazone may decrease. Rosuvastatin no effect on heart failure + atorvastatin helps heart failure. Only yo

Pharmacology 4350A/B Lecture Notes - Lecture 9: Theralizumab

Belmont report - guiding principles for human research. Clinical equipoise - honest genuine uncertainty of the drug in question and comparator drug goi

Pharmacology 4350A/B Lecture Notes - Lecture 8: Rifabutin, Bosentan, Muromonab-Cd3

Fda sped up process in 1990 + biopharmaceutical in 1980. High throughput screening assays best serves this strategy. Automated system in conducting che

Pharmacology 4350A/B Lecture Notes - Lecture 8: Theralizumab, Mibefradil, Torcetrapib

Phase 2 - broad end points to look at everything. Phase 3 - narrow end points and more clinical end points. Some illness heal on its own + illness come

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