asiaal

In a post that is a minimum of 150 words, respond to the following: What are your initial reactions and observations of the case? Mr. Smith was diagnosed with sickle cell anemia. He has an ulcer in the medial side of his ankle. How would the condition of the red cells contribute to what the patient suffers from? How would you describe inflammation? How do you recognize that Mr. Smith has an inflammatory response? Is inflammation always bad? Do you know of any white cell disease that reduces our inflammatory response? Mr. Smith is allergic to penicillin and iodine. What do you know about allergies? What type of hypersensitivity is it? Mr. Smith's mother had a right radical mastectomy due to breast cancer. How would you define a malignant tumor? How would you differentiate a cancerous tumor from a benign tumor?

case study:

Personal Information

Name: Mr. Peter Smith

Age: 45 years old

Gender: Male

Description

Mr. Peter Smith came to the medical office complaining of fatigue, asthenia, headaches, and generalized abdominal pain. Our patient tells us that he has had a high fever, but he did not take his temperature. The patient has had previous episodes of abdominal pain and arthralgia. Also, he was diagnosed with sickle cell anemia when he was a child. His father suffers from sickle cell anemia, diabetes mellitus, and essential hypertension. Our patient’s mother had a right radical mastectomy due to breast cancer a few years ago, and she suffers from sickle cell anemia, like Mr. Smith and his father. There is no other remarkable pathologic family history.

Mr. Smith drinks alcohol at least once per month and smoke cigarettes. He has no history of drug addiction. He is allergic to penicillin and iodine.

On physical examination we found:

Remarkable Signs on Physical Exam by Regions

• Abdomen: Distended and painful on palpation, mostly on the left upper quadrant. Splenomegaly.
• SOMA: Joint pain

Remarkable Signs on Physical Exam by Systems

• Integumentary system: Yellowish skin and pale nail beds. Superficial crater-like skin lesion on the right medial ankle area. An erythematous area accompanied by edema, purulent secretion, and heat surrounds the lesion.
• Respiratory system: Tachypnea
• Cardiovascular system: Tachycardia

Lab Tests

• Complete blood count (CBC)
• Hemoglobin electrophoresis
• Abdominal ultrasound
• EKG

Supporting Material

In order to understand Mr. Smith's case, we need to investigate the primary concepts of homeostasis at a cellular level and explore specific conditions when homeostasis is not present. How does our body adapt to environmental toxins? We will explore this question by looking at specific outcomes when there are deviations from homeostasis in three specific areas:

• Cellular adaption and neoplasia
• Infection, immunity, and inflammation
• Hematological disorders

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