Problem 3

Background and context

Protein synthesis begins with the association of the translation initiation complex. In eukaryotes, the binding of the methionine-tRNA to the 40s ribosome initiates protein synthesis and it is by a protein initiation factor called the eukaryotic initiation factor -2 (eIF-2).  This tRNA binds to the high-energy molecule guanosine triphosphate (GTP).