IMED1001 Study Guide - Final Guide: Osmotic Concentration, Tonicity, Extracellular Fluid
Document Summary
An iso-osmolar solution is not always isotonic. Because diffusion of osmotic solutes occurs over time. Solute transport across membranes is essential for cell function. Passive diffusion occurs from random movement of molecules down their concentration gradient. Membrane permeability is influenced by molecular weight, lipid solubility and charge. Water movement (osmosis) across membranes is important for. Volume of extracellular compartments e. g. blood plasma, interstitial fluid. Membranes have channels to allow certain molecules to break the rules. Diffusion of h2o from an area of higher h2o concentration to an area of lower h2o concentration. The total solute concentration of a solution and relates to the number of particles per litre (osm). 1 osm = 1 mole of particles per litre. Particles include any ions such as na+, cl- and ca2+ and any molecules such as glucose or amino acids. & 1osm cl- in solution = 2 osm. Has a lower osmolarity than another solution or cell cytoplasm.
