IMED3001 Study Guide - Midterm Guide: Hypereosinophilic Syndrome, Restrictive Cardiomyopathy, Sarcoidosis

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Abnormal diastolic function with excessively rigid left ventricular wall which impedes ventricular filling during diastole. Diseases that affect the myocardium such as amyloid disease of the heart, radiation fibrosis, sarcoidosis, metastatic tumours or deposition of metabolites. Fibroelastic thickening of the endocardium of the left ventricle. Occurs in young people in africa and consists of fibrous thickening of endocardium and inner myocardium of the inflow tract of left ventricle. Endomyocardial fibrosis associated with eosinophilia from any cause (parasites, eosinophilic leukaemia) Mural thrombi are a complication in all these conditions. Ventricles are approximately normal size or slightly enlarged and the cavities are not dilated and the myocardium is firm and non compliant. Patchy or diffuse interstitial fibrosis which can vary from minimal to extensive. Myocarditis: inflammation of myocardium, can result in cardiac failure or sudden death, can affect previously well fit persons. Rickettsial (typhus, rocky mountain spotted fever)

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