HUMB2009 Final: RESPIRATORY 3 (GRANULOMATOUS DISEASES)
Document Summary
Both are granulomatous diseases which involve masses of immune cells @ sites of infection or inflammation, but. Need mucous analysis to be able to distinguish, there is a high prevalence of tb in. Sarcoidosis is present with non-caseating epitheloid cell granuloma, no necrosis developing countries which makes it even harder. Exclusion of tb is important because corticosteriods are the main treatment for. Can involve gi, gu and skeletal systems. Primary pulmonary tuberculosis bacterial infection starts it: patchy/lobar 1 sided consolidation, necrosis, hilar and mediastinal adenopathy, unilateral, calcification of nodes, atelectasis, pleural effusion. Post primary tuberculosis : apical areas, patchy/lobar consolidation, hilar nodal enlargement, cavitation. Miliary tuberculosis dissemination by blood stream: fine nodules diffuse bilaterally. Consolidation lobular or segmental/patchy, homogenous and dense. Thickening of bronchovascular bundle and peri lymphatic distribution of nodules that represent the sarcoid granuloma. Central- low attenuation necrotic lymphadenopathies with peripheral (rim) enhancement. Miliary diffuse, bilateral millet seed-sized nodules. Right upper lobe consolidation, with intrinsic cavitation.