HSE201 Study Guide - Final Guide: Creatine Kinase, Endoplasmic Reticulum, Pyruvate Dehydrogenase

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Relation time increased/prolonged due to slowed rate of ca2+ re-uptake at sarcoplasmic reticulum (sr) Intramuscular k+ loss, due to compromised na+/k+ pump function from decreased. Elevations in pi inhibit binding of ca2+ to troponin. Energy crisis atp demand cannot be matched atp production. Lack of carbohydrate stores required for prolonged exercise. Increased cho oxidation, produces by-products a ecting fatigue. Provide and overview of energy metabolism via 3 systems. *breaking down of fuels creates energy for resynthesis of atp producing energy. Pcr requires atp (reversed reaction) therefore reformation occurs primarily during recovery. Pcr + adp (creatine kinases) atp + cr (free) Anaerobic breakdown of glucose or glycogen, often to form lactic acid. Conditions of reaction result in formation of lactic acid. Provides rst phases of aerobic oxidation during low intensity work. Oxidation of glucose: c6h12o6 + 6o2 +32(adp + pi) 6h2o + 6co2 + 32atp. Oxidation of glucose occurs in 4 stages: glycolysis.

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